Author Archives: Mark Peplow

C&EN: Click and bioorthogonal chemistry win 2022 Nobel Prize in Chemistry

Carolyn R. Bertozzi, Morten Meldal, and K. Barry Sharpless receive prize for their work on reactions that quickly link up molecules and their application in living cells.

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C&EN: Blue-light special offers sweeter route to 𝐶-glycosides

Glycosyl sulfones need no catalyst for light-triggered radical coupling.

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C&EN: Molecular containers go supersized

Large macrocycle offers wider base for record-breaking cavitands that can trap and separate fullerenes.

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C&EN: Cyclodextrins line up for better filtration membranes

Porous films can separate molecules such as cannabidiol from organic solvents.

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C&EN: New form of lithium reacts 20 times as fast as powdered metal

Crystallized dendrites offer high purity and surface area when preparing organolithium reagents.

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C&EN: Perfluorinated ligand makes long-awaited debut in rhodium complex

After a 40-year wait, fully fluorinated cyclopentadienyl derivative finally connects with a metal partner.

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C&EN: Paper strip detects SARS-CoV-2 variants

Foldable assay could help track different COVID-19 mutants for low-cost surveillance.

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C&EN Talented 12: Ming Joo Koh

This organic chemist uses common metals to shrink synthetic chemistry’s environmental footprint.

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C&EN Talented 12: Weixue Wang

This assay inventor identifies drug candidates for targets once thought to be undruggable.

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C&EN: Nickel catalyst enables versatile amine synthesis

Method creates hundreds of different amines from handy nitriles.

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